# @realdavefeldman on YouTube

- **Type:** Video
- **Original URL:** https://youtube.com/watch?v=cM0KaSp5IIE
- **Gondola URL:** https://gondola.cc/posts/30285571-realdavefeldman-youtube
- **Thumbnail:** https://img.gondola.cc/tr:w-,h-,fo-auto/postThumbnails/33d93d45c6.jpg
- **Posted:** 2025-05-08T14:32:28.000+00:00
- **Account Owner:** Dave Feldman (@realDaveFeldman) — https://gondola.cc/realDaveFeldman

## Caption

Dave Feldman sits down with Chris MacAskill to unpack the Keto-CTA study: owning key mistakes, dissecting plaque progression metrics, and charting the path forward in lipid research. Along the way, they explore observational data limits, AI-guided imaging, and the role of community and social media in driving scientific discovery.

Chapters
00:00 Intro & Study Context
00:04 Acknowledging Mistakes & Team Dynamics
01:03 Figure 1A Graphical vs Numerical Error
03:09 Importance of Table 3 & Endpoint Inclusion
05:00 Heterogeneity in Non-Calcified Plaque Progression
07:47 Observational Data & Causation Debate
11:13 What Is Percent Atheroma Volume (PAV)?
15:00 Semi-Quantitative vs Quantitative Metrics
16:15 Cohort-Wide 50 % Increase in PAV
18:06 Biology vs Algorithm in AI Readings
20:59 Comparison with Miami Heart Cohort
25:30 Why a Control Group Was Challenging
30:00 Sources of Saturated Fat & LDL Impact
34:00 Lean Mass Hyper-Responder Physiology
40:00 Protein Shake Rate-of-Change Analogy
44:00 LDL/ApoB Predictive Power Discussion
47:00 Social Media’s Role in Research Funding
51:17 Epistemic Humility & Next Paper Plans
56:49 Team Recognition & Second Study Fundraising
1:00:05 Silver Linings & Journal Correction Practices
1:06:17 Closing Remarks & Upcoming Topics

#Cholesterol #LDL #KetoDiet #ApoB #CAC #CCTA #LMHR #LEM #SaturatedFat #HeartHealth #MetabolicHealth #Educational #StayCurious #Wellness #Fitness #CardiovascularRisk #KetogenicDietSafety #HeartDisease #CholesterolManagement #Ketosis #CardiovascularHealth #MetabolicSyndrome #FattyAcidMetabolism #Atherosclerosis #PlaqueProgression #LDLCholesterol #ApoBLevels #HealthyHeart #DietaryFats #HeartDiseasePrevention #StatinAlternatives #KetoHeartHealth #KetoStudies #HealthResearch #HealthAndWellness #CardiovascularDiseasePrevention #CholesterolResearch #KetogenicLifestyle #HeartWellness #ScienceBasedHealth

## Stats

- **Views:** 12,258
- **Likes:** 477
- **Shares:** 0
- **Comments:** 446

## Tags

metabolicsyndrome, plaqueprogression, ldl, ketosis, ketodiet, dietaryfats, ketogenicdietsafety, ccta, metabolichealth, ketogeniclifestyle, hearthealth, cholesterolmanagement, cholesterolresearch, apoblevels, wellness, healthandwellness, cardiovascularhealth, cardiovasculardiseaseprevention, heartdisease, healthyheart, healthresearch, ketostudies, heartdiseaseprevention, educational, cac, ketohearthealth, sciencebasedhealth, cardiovascularrisk, apob, staycurious, lem, statinalternatives, lmhr, atherosclerosis, ldlcholesterol, cholesterol, fitness, saturatedfat, heartwellness, fattyacidmetabolism

---
Copyright (c) Gondola