# @mackinprof on Instagram

- **Type:** Image
- **Original URL:** https://www.instagram.com/p/DLR-k3ZP8g5
- **Gondola URL:** https://gondola.cc/posts/59739431-mackinprof-instagram
- **Thumbnail:** https://img.gondola.cc/tr:w-,h-,fo-auto/postThumbnails/a11ce9c353.jpg
- **Posted:** 2025-06-24T10:53:55.000+00:00
- **Account Owner:** Stuart Phillips (@mackinprof) — https://gondola.cc/mackinprof

## Caption

📈 MORE VOLUME = MORE GAINS?

After reviewing hundreds of studies, gregnuckols wrote a brilliant treatise on training volume and hypertrophy for strongerbyscience. For more articles like this one, subscribe to massresearchreview (I'm a subscriber!). Huge kudos to Greg, and I agree with (almost 😉) everything he says! Quick post about a great article that for many will be TLDR (but it's worth the time IMO).

✅ Higher training volumes increase hypertrophy – even beyond 20 sets/week per muscle group. There's no clear “max” where benefits stop. I think that ultrasound data has added some noise into the curve, and that with better methods, you'd see growth stop much earlier than seen in https://doi.org/10.51224/SRXIV.460

✅ Strength plateaus ≠ hypertrophy plateaus. Some claimed that since strength gains level off around 5 sets per week, hypertrophy must also. But this idea is flawed – they rely on different data and mechanisms. GREAT take and spot on!

✅ Swelling ≠ Muscle Growth. The myth that “more growth at high volumes is just muscle edema” doesn’t hold. Over time, the swelling disappears while the muscle continues to grow. I grew tired of this argument, and Greg deservedly buries it!

✅ Individual responses vary. Some grow more with high volume, others don’t. But on average, more volume = more gains (at least to a point)

✅ My note on sarcoplasmic hypertrophy - if it happens, it's transient, if it's transient, it's also small, and so it is NOT a big contributor to 'growth.' I love the theory of the pre-priming for growth, but there's very little data to support how this would take place at a cellular level - see PMID 32660165

🧠 Final takeaway: Want to grow more? You probably need to do more. 10 sets/week is fine. 20–30? Even better for some.

Citation (and kudos): Nuckols G. More Training, More Gaining (2024)

#Hypertrophy #StrengthTraining #MuscleGrowth #TrainingVolume #EvidenceBasedTraining #ScienceOfStrength #scienceofstrengthtraining

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## Tags

evidencebasedtraining, scienceofstrength, trainingvolume, musclegrowth, strengthtraining, scienceofstrengthtraining, hypertrophy

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