Understanding how mitochondria and lysosomes interact within cells could make a big difference for people living with neurodegenerative and metabolic diseases. David Shackelford, Roberto Zoncu and Rushika Perera are using advanced techniques to create detailed maps of how mitochondria and lysosomes work together to manage energy in both healthy and diseased cells. These maps highlight differences between healthy tissues and those affected by disease and could potentially guide the development of targeted therapies for metabolic and neurodegenerative diseases. #CellScience #CellBiology #science #biology #microscopy