Kristina Manners reviews our #1 Best-Selling Serum. The Shiseido Ultimune Power Infusing Serum is a potent antioxidant face serum with a lightweight formula that visibly reduces signs of aging, amplifies hydration, and boosts radiance in 3 days. How To Use: Use Ultimune after cleansing and softening skin, but before applying any other serums or moisturizers. Pump twice onto your fingertips and smooth evenly over your face and neck. Use Ultimune twice daily, morning and night. FOR REFILL: Save the pump and cap from your original bottle. Insert the pump into the refill, then close the cap. Shop Shiseido Ultimune now: bit.ly/3qmyjox #Ultimune #Shiseido @kristina.manners