According to 2024 Patient Registry data, the median predicted age of survival for people with cystic fibrosis born in the U.S. between 2020-2024 is estimated to be 65 years of age. We are proud to see this figure reach 65 years and celebrate this continued improvement. However, we recognize that many people with CF, particularly those who do not benefit from modulators and those living post-transplant, may have shorter lives. In addition, this prediction does not apply to people with CF born before 2020. We also know quality of life — and not just quantity — is incredibly important. We have important, urgent work ahead of us. You have helped us achieve this milestone, but we are far from done. We remain laser-focused on developing transformative treatments and finding a cure for all people with cystic fibrosis. We won’t settle for anything less.