UPDATE: 49ers HC Kyle Shanahan estimated today to reporters that WR Brandon Aiyuk — who is recovering from a significant knee injury — could be back for Week 6. adamschefter #49ers • • FOLLOW 🏈 • • #49er #49ersforlife #49erempire #49erfaithful #ninerempire #ninernation #fttb #questforsix #foreverfaithful #goniners #goniners🏈 #bangbangninergang #bangbangninergang🏈 #sf49ers #nfl #nflfootball #ninerfan #ninerfam #brockpurdy #brandonaiyuk #sanfranciso #georgekittle #faithfull #collegefootballhighlights #nflhighlights #bayarea #goldenstate #goldenstatewarriors #ninergang