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The deadliest animal on Earth fits on your fingertip. Mosquitoes may be small, but the diseases they spread have an enormous impact on families and communities worldwide. 🦟 🌎 At UC San Diego, researchers are reimagining how we prevent mosquito-borne disease by engineering genetic tools that stop transmission before it ever reaches a person. In the School of Biological Sciences, scientists like molecular biologist Omar Akbari are developing new approaches that target the mosquitoes responsible for most malaria transmission, especially as resistance reduces the effectiveness of traditional tools. Recent discoveries show just how powerful these ideas can be. In 2025, UC San Diego biologists identified a genetic change that prevents the malaria parasite from reaching a mosquito’s salivary glands. The mosquito can still bite, but it can no longer spread the disease. Together, these advances point to a future where protecting vulnerable communities and eliminating diseases like malaria ...

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