If your antidepressant feels like it’s doing… nothing, there may be a missing piece. Some people carry variants of the MTHFR gene that make it harder to convert folic acid into the active form needed for the one-carbon cycle — a pathway required to produce serotonin and other neurotransmitters. If that pathway is sluggish, SSRIs like Lexapro, sertraline, or Prozac may not work as well. Clinical research shows that adding 15 mg of L-methylfolate, the bioactive form of folate, can significantly improve response in certain patients. Before assuming the medication failed, it may be worth discussing nutrient support and genetic factors with your provider. Better chemistry can mean better results. 👉👉👉Comment FOLATE if you want more info. #philsmypharmacist #mthfr #mthfrawareness #mthfrgenemutation #methylfolate ***Educational only. Always talk with your healthcare provider before making changes.