What if we could keep a timeline of gene activity inside cells? Many important biological processes, such as learning in brain cells or changes in cancer cells, depend on how gene activity evolves over time, not just at a single moment. Most tools that capture that information either require constant live imaging, which is hard to maintain, or they destroy the cell and lose important information. This colorful image shows CytoTape inside a cell. Cytotape keeps a physical record of gene activity over time and works by building a long, flexible protein where different parts of the strand can mark when and how strongly certain genes were active. Out in Nature today, this foundational work moves us closer toward better understanding learning, memory, and aging. 👏 Congrats to the team, including Biohub grantees Changyang Linghu and Denise Cai. #imaging #science #biology #neuroscience