Weight loss in perimenopause: the laws of physics still work! Hormonal shifts aren’t destiny—energy balance rules!! • Macdonald et al. (2003) 1,064 women (45–54 y) followed for 6.3 ± 0.6 y. ↓ Energy expenditure explained most weight gain; dietary calcium and HRT had no effect. Int J Obes Relat Metab Disord. 2003;27(6):669–676. PMID: 12833110; DOI: 10.1038/sj.ijo.0802283 • Williams et al. (2014) “40-Something RCT”: 12-mo trial in late pre-/early perimenopausal women (mean 47.3 y; BMI 25.1 kg/m²). Five MI consultations vs self-directed materials—The MI (motivational interviewing) group lost ~2.6 kg and lowered diastolic BP. Nutr Diabetes. 2014;4:e116. PMID: 24799163; DOI: 10.1038/nutd.2014.12 • Hao et al. (2022) 78 perimenopausal women randomized to (A) education only, (B) diet, or (C) diet + supervised resistance exercise for 3 mo. Groups B & C saw ↓ BMI, trunk fat, and waist circumference; group C also ↑ lean mass. Front Nutr. 2022;8:752500. PMID: 35155511; DOI: 10.3389/fnut.2021.7...