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By simultaneously recording from two DBS targets — the centromedian thalamus (CM) and anterior globus pallidus internus (aGPi) — Fixel Institute researchers uncovered new insights into how tics begin. “Interestingly, this intra-hemispheric coordination contrasts with expectations from other disorders like tremor, and our findings help decode how specific brain networks contribute to tic generation. This study adds crucial evidence to the growing field of adaptive DBS, highlighting where and when to target intervention during tics.” — Grace Lowor, Biomedical Engineering PhD student Read more about this groundbreaking study: movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.70043 #Neuroscience #TouretteSyndrome #DBSResearch

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