Aesthetic medicine is entering a domain that, until recently, belonged exclusively to internal medicine and longevity science. At AMWC Monaco I sat down with Valerie Matamo, President of corporationvm Corporation, to talk about hack.yourskin V-Hacker and why mitochondria are becoming a primary therapeutic target in aesthetics. What does that mean clinically? GHK-Cu is a copper tripeptide that activates TGF-β and stimulates fibroblasts to produce type I and III collagen. It acts as a free radical chelator and modulates the expression of repair genes, including MMPs responsible for extracellular matrix remodeling. The result: improved skin density and faster recovery after ablative procedures. Epitalon is a tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase the enzyme responsible for maintaining telomere length in dividing cells. Shorter telomeres mean accelerated replicative aging of fibroblasts. Epitalon slows this process, extending the biological regenerative potential of the t...