🔎 Today’s Daily Sift: Longevity Longevity is moving upstream. A new study found that a blood test measuring p tau217 may help identify healthy older adults at high risk of developing Alzheimer’s symptoms years later. People with very elevated levels had a 38 percent risk of cognitive impairment within five years and a 78 percent risk within ten years. The test is not ready for routine prediction yet. But the signal is powerful. Medicine is learning to detect neurological decline before memory fails. Biogen also reported that its experimental drug diranersen reduced toxic tau protein by as much as 65 percent. The trial produced mixed cognitive results, but it suggests that gene silencing may alter one of Alzheimer’s core biological drivers. Then came the warning from the GLP 1 revolution. A study of nearly 30,000 tirzepatide users found that older adults who developed malnutrition, dehydration, or muscle loss faced sharply elevated health risks. That is the part the scale c...