Which medicines offer the greatest benefits for adults living with overweight or obesity? Our Mid-month Essential Knowledge Update (EKU) explores the latest evidence from a British Medical Journal systematic review and network meta-analysis, comparing the benefits and harms of medicines used to manage overweight and obesity. With obesity affecting more than 890 million adults worldwide, keeping up with the evolving evidence can support informed conversations and shared decision-making with patients. Visit our website to read the latest EKU Hot Topic and stay up to date. ⤵️ elearning.rcgp.org.uk/mod/page/view.php?id=17049 #RCGP #EKU #Obesity